Thrombocytopenia (ITP, drug-induced, malignancy)

Thrombocytopenia = low platelet count → increased mucosal/procedural bleeding risk. Dental planning is driven by: (1) platelet count TREND + bleeding history (trend matters more than any single value), (2) procedure bleeding risk (non-invasive vs invasive), (3) cause (ITP, chemo, drug-induced, marrow failure/malignancy) and co-medications. Key point: published platelet thresholds (including the commonly quoted ~50k figure) rest on low-certainty evidence and expert consensus — they are guidance RANGES, not hard universal cut-offs. Bleeding risk rises as counts fall but is often manageable with local hemostatic measures and hematology coordination. Use the numbers below as starting points for discussion with the patient's hematologist, not as automatic go/no-go rules.