Organ transplant recipients

Transplant recipients are chronically immunosuppressed → higher risk of: (1) severe infection from odontogenic sources, (2) impaired wound healing, (3) oral opportunistic infections + increased malignancy risk. KEY DENTAL PRINCIPLE: treat stable patients routinely with strong infection source control and DRUG-INTERACTION AWARENESS; coordinate with the transplant team for complex surgery or early post-transplant periods. CRITICAL INTERACTIONS: tacrolimus/ciclosporine + clarithromycin or erythromycin → calcineurin-inhibitor toxicity, so avoid these (azithromycin is the lower-risk macrolide if one is genuinely needed); + systemic azole antifungals → avoid unless the transplant team manages levels. This is the generic solid-organ-transplant card — see the organ-specific card (renal / cardiac) for graft-specific detail.